Jane Mellor

Professor Jane Mellor is a lecturer and full professor in the Department of Biochemistry at Oxford University. She established her research group to focus on gene expression and chromatin and has more recently uncovered linked between chromatin, transcription and RNA fate, and between chromatin and metabolism. The group has pioneered understanding the role of non-coding transcription, demonstrating roles in switching chromosome conformation signatures to coordinate gene expression with metabolism and to altering chromatin structure over genes. Lately, the group had applied mathematical modelling to  uncover fundamental relationships in transcription that are beyond the resolution of current experimental techniques for yeast and mammalian cells. Jane has contributed to three local spin-out companies: Oxford BioDynamics plc (OBD), Chronos Therapeutics Ltd. and Sibelius Natural Products Ltd, all with discoveries made first in yeast underpinning their technology. 

Lab page link: https://www.bioch.ox.ac.uk/research/mellor