Erik Sahai

Erik Sahai is the head of the Tumour Cell Biology laboratory at the Francis Crick Institute in London. Erik obtained his PhD with Richard Treisman in London studying RhoGTPases and their effectors. He then carried out post-doctoral work in both London (Chris Marshall) and New York (John Condeelis). Following this training, Erik set up his own group at the Cancer Research UK London Research Institute in 2004 and then transferred to the Francis Crick Institute in 2015. His research is focused on the spread of cancer through the body and responses to cancer therapy. In particular, his group is interested in stromal fibroblasts and their interplay with both tumour and immune cells. To study these problems his group uses a wide range of techniques from computational modelling of cell migration, through conventional cell and molecular biology, to intravital imaging of mouse tumours and live analysis of patient derived material.

Erik’s contributions have been recognised by the award of the Hooke Medal, and election to EMBO, the European Academy of Cancer Sciences, and the Academy of Medical Sciences. He is president elect of the Metastasis Research Society and serves on the editorial board of several journals, including Journal of Cell Biology, Developmental Cell, and Trends in Cell Biology.

Research Interests: tumour microenvironment, optical imaging, cell-cell communication, metastasis, therapy failure and cancer evolution

https://www.crick.ac.uk/research/labs/erik-sahai

https://twitter.com/eriksahailab