Clare Bryant

Clare Bryant is Professor of Innate Immunity at the Departments of Medicine and Veterinary Medicine in the University of Cambridge.  She studies innate immune cell signalling in response to Pathogen Associated Molecular Pattern Receptor (PRR) activation during bacterial infection using cutting edge multi-disciplinary approaches (collaborating with mathematicians, physicists, physical chemists and structural biologists) to answer fundamental questions about host-pathogen interactions and how to modify them therapeutically.  She also applies these innovative approaches to study PRR-induced inflammatory signalling in chronic diseases of humans and animals.  In particularly her work using super resolution, single molecule fluorescent imaging and cryo electon tomography approaches to study Toll-like receptor and NOD-like receptor signalling within cells have revealed novel mechanisms in how these receptors signal.